What are targeted therapies for ovarian cancer?
Cancer occurs when genetic mutations in our cells cause them to multiply uncontrollably and accumulate to form a tumour.
Targeted cancer therapies are drugs that can stop the spread of cancer by identifying and blocking the genetic changes responsible for the cancer’s growth and spread. They are designed to target cancer cells while reducing the damage to normal, healthy cells.
There are different targeted therapies available to women with ovarian cancer. Find out more about these medicines and how they work below.
High Grade Serous Cancer
Low Grade Serous Cancer
Who decides which of these drugs I can take?
Access to targeted therapies is decided by different bodies depending on where in the UK you live.
In England, which drugs are available on the NHS is decided by National Institute for Health and Care Excellence (NICE).
In Wales, generally the guidance produced by NICE is followed but this is overseen by the All Wales Medicines Strategy Group (AWMSG)
In Northern Ireland, the Department of Health makes decisions, but they often follow NICE.
In Scotland, the Scottish Medicines Consortium (SMC) makes decisions about NHS Scotland and this is not related to NICE decisions.
Targeted treatments for ovarian cancer are available in specific situations, depending on the type and stage of your cancer, results of tumour testing and also other health issues you may have. The guidelines and eligibility can be very confusing. Your cancer team will be able to talk you through what you may be eligible to take and when. If there isn’t access through standard channels, they may also be able to advise you on trials that could be available based on your diagnosis.
Questions to ask your team
- What options are available to me?
- What are the risks and benefits of each option?
- How long will I be able to take this medication?
- What side effects are most likely to happen?
- What side effects are more serious to look out for?
- Who do I contact if I am worried about side effects?
- How do we know this treatment is working?
- What happens if the treatment isn’t working?
- What are my options if I choose not to have one of these treatments?