How can we prevent spread and recurrence of ovarian cancer?

Professor Ahmed Ahmed, Weatherall Institute of Molecular Medicine, University of Oxford 

Eradicating cancer completely through chemotherapy is difficult and in many cases, invisible cancer cells remain in the body. With each round of treatment the tumour is more likely to become resistant to chemotherapy. Professor Ahmed’s team is working to test if high grade serous ovarian cancer can evolve to become sensitive again. The team is also investigating how an enzyme called SIK2 helps ovarian cancer cells spread throughout the abdomen by relaying signals from fat cells in the omentum to the tumour. 

What’s next?

Professor Ahmed’s team aims to use their new insights into ovarian cancer behaviour in order to develop new treatments that will stop the disease in its tracks and eliminate ovarian cancer cells that remain after treatment.